Replication data for - Incidence of loiasis clinical manifestations in a rural area of the Republic of Congo: results from a longitudinal prospective study (the MorLo project) (doi:10.23708/BNMZN8)

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Part 2: Study Description
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Replication data for - Incidence of loiasis clinical manifestations in a rural area of the Republic of Congo: results from a longitudinal prospective study (the MorLo project)

doi:10.23708/BNMZN8

DataSuds

2025-01-30

1

Campillo, Jérémy; Pakat-Pambou, Biam-Miveck; Sahm, Bachiratou; Pion, Sebastien D. S.; Hemilembolo, Marlhand C.; Lebredonchel, Elodie; Boussinesq, Michel; Missamou, François; Chesnais, Cédric, 2025, "Replication data for - Incidence of loiasis clinical manifestations in a rural area of the Republic of Congo: results from a longitudinal prospective study (the MorLo project)", https://doi.org/10.23708/BNMZN8, DataSuds, V1, UNF:6:ot97WXQ0SsOwXC4RC0YeHw== [fileUNF]

Replication data for - Incidence of loiasis clinical manifestations in a rural area of the Republic of Congo: results from a longitudinal prospective study (the MorLo project)

doi:10.23708/BNMZN8

Campillo, Jérémy (UMI TransVIHMI - IRD, INSERM, Univ. Montpellier - France)

Pakat-Pambou, Biam-Miveck (Hôpital de base de Sibiti - , Brazzaville - Republic of Congo)

Sahm, Bachiratou (UMI TransVIHMI - IRD, INSERM, Univ. Montpellier - France)

Pion, Sebastien D. S. (UMI TransVIHMI - IRD, INSERM, Univ. Montpellier - France)

Hemilembolo, Marlhand C. (Programme National de Lutte contre l'Onchocercose, Direction de l'Épidémiologie et de la Lutte contre la Maladie, Ministère de la Santé et de la Population, Brazzaville - Republic of Congo)

Lebredonchel, Elodie (Département de Biochimie, Hôpitaux Universitaires Paris Nord Val de Seine – site Bichat, Assistance Publique des Hôpitaux de Paris - France)

Boussinesq, Michel (UMI TransVIHMI - IRD, INSERM, Univ. Montpellier - France)

Missamou, François (Programme National de Lutte contre l'Onchocercose, Direction de l'Épidémiologie et de la Lutte contre la Maladie, Ministère de la Santé et de la Population, Brazzaville - Republic of Congo)

Chesnais, Cédric (UMI TransVIHMI - IRD, INSERM, Univ. Montpellier - France)

949963

DataSuds

Campillo, Jérémy

Campillo, Jérémy

2025-01-27

https://doi.org/10.23708/BNMZN8

Medicine, Health and Life Sciences, Loiasis, Filariasis, Multiple failure analysis

Medical entomology, parasitology and virology

<p>Loiasis is endemic in Central Africa. Despite evidence of clinical complications and increased mortality, it remains excluded from the list of neglected tropical diseases. The main manifestations are Calabar swellings (CS), Eyeworm (EW) and non-specific general symptoms such arthralgia and pruritus.</p> <p>We calculated incidence rates for clinical manifestations of loiasis from a 13-month study on clinical manifestations in 991 individuals living in Loa loa-endemic areas in the Republic of Congo.</p> <p>From September 2022 to September 2023, community health workers collected weekly symptoms from cohort participants. Detailed data on symptom duration, intensity, associated pruritus, and impact on sleep were recorded. Laboratory procedures included thick blood smear for L. loa microfilaremia measurement, creatininemia measurement and eosinophilia counts. We used multiple failure analysis and frailty models to calculate incidence rates of EW, CS, arthralgia, pruritus and absence from work (AfW) and to analyses factors associated with increased incidence of each symptom. The population-attributable fractions (PAFs) associated with loiasis were also calculated for pruritus, AfW and arthralgia.</p>

2022-09-01-2023-09-01

Congo

Lékoumou, Sibiti

• West Bounding Longitude: 12.598888397216797
• East Bounding Longitude: 14.34555435180664
• South Bounding Latitude: -4.054166793823242
• North Bounding Latitude: -2.088889122009277

Data Type: Observational data

This dataset is sensitive because it contains personal health data that are potentially identifying. Any attempt to re-identify participants is strictly prohibited. Data is available upon request to the authors. Access to the data is subject to approval and a data sharing agreement.

• Number of cases: 318

• No. of variables per record: 13

• Type of File: text/tab-separated-values

UNF:6:dFCLcW0hIoweFRZXnUre5Q==

• Number of cases: 590

• No. of variables per record: 14

• Type of File: text/tab-separated-values

UNF:6:KsyMzOWdFmTg5IqD70Qiuw==

• Number of cases: 991

• No. of variables per record: 7

• Type of File: text/tab-separated-values

UNF:6:uIzri/nwGgE5Jup+He9G2w==

• Number of cases: 284

• No. of variables per record: 13

• Type of File: text/tab-separated-values

UNF:6:Iumba8EBvPLihiiBMY213A==

• Number of cases: 228

• No. of variables per record: 17

• Type of File: text/tab-separated-values

UNF:6:/Jlkuj59CZ9P6Fostsl31A==

• Number of cases: 354

• No. of variables per record: 14

• Type of File: text/tab-separated-values

UNF:6:mTHXzl8TAI4HikJHGY7dhw==

• Number of cases: 77

• No. of variables per record: 4

• Type of File: text/tab-separated-values

UNF:6:h3AbjxRFErQOpCOBZJWQgA==

• Variable name - Variable name
• Meaning of the variable - Meaning of the variable
• Unit of measurement - Unit of measurement
• Codes - Codes

f45635 Location:

Variable Format: character

Notes: UNF:6:2LKWrjnaA8EguO+s7j5ULg==

f45635 Location:

Variable Format: character

Notes: UNF:6:FMuK/ZBESwQVv/QrTbsJmQ==

f45635 Location:

Variable Format: character

Notes: UNF:6:hNXLE//3DerXF0LO5yl1uA==

f45635 Location:

Variable Format: character

Notes: UNF:6:zdH3AyqrObvo573pkFFmng==

Label:

Incidence_loiasis_Data_collection_questionnaire.pdf

Text:

Data collection questionnaire (in english)

application/pdf

Label:

Incidence_loiasis_Questionnaire_recueil.pdf

Text:

Questionnaire de recueil des données (en français)

application/pdf

Label:

Incidence_loiasis_ReadMe.txt

Text:

Dataset citation, description and terms of use

text/plain