Passive case detection of Human African Trypanosomiasis in Côte d’Ivoire

Version 2.1

Lejon, Veerle; Kaba, Dramane; Kabore, Jacques; Buscher, Philippe; Kone, Minayégninrin; Kouame, Cyrille Mambo; Compaore, Charlie Franck Alfred; Jamonneau, Vincent, 2021, "Passive case detection of Human African Trypanosomiasis in Côte d’Ivoire", https://doi.org/10.23708/FNZDMZ, DataSuds, V2, UNF:6:h9Cy8G5/SAO4IaPoWCW0zg== [fileUNF]

Learn about Data Citation Standards.

Contact Owner

Dataset Metrics

56 Downloads

Description	In the last decade, the prevalence of Trypanosoma brucei gambiense human African trypanosomiasis (HAT) has fallen and HAT has been targeted for elimination. At low disease prevalence, integration of case finding into routine activities of peripheral health centres becomes crucial. However, HAT case detection by the peripheral health system with limited resources requires adapted diagnostic tests and test algorithms. The objective of the DiTECT-HAT-WP2 study was to determine the diagnostic performance and cost of rapid diagnostic tests (RDTs) performed on clinical suspects in peripheral health centres, whether or not followed by serological and/or molecular tests on filter paper done at regional reference centres. DiTECT-HAT has been registered in clinicaltrials.gov under ID NCT03356665, and is part of the DiTECT-HAT project, funded by EDCTP2-Horizon 2020- European Union. The DiTECT-HAT-WP2 study was conducted in centres for diagnosis and treatment and in sites for serological screening in Guinea, Côte d’Ivoire and DR Congo. In these centres and sites, clinical suspects were tested with several commercially available RDTs for HAT. Clinical suspects with at least 1 RDT positive result, 1° underwent parasitological examination and 2° blood collection on filter paper for reference analysis in trypanolysis, LAMP, ELISA and real-time PCR in the regional reference laboratory. If the reference laboratory tests and parasitological examinations were all negative, the suspect was considered free of HAT. If at least 1 reference test was positive, parasitological examinations were repeated at least twice at three months interval, unless trypanosomes were detected. The deposited file contains the DiTECT-HAT-WP2 study protocol in French and English, the informed consent form, and metadata of DiTECT-HAT-WP2 in Côte d'Ivoire. DiTECT-HAT-WP2 data will be made available to qualified researchers upon request after signing a confidentiality agreement. Data requests may be sent to the coordinating investigator (for coordinates see study protocol, Institut de Recherche pour le Développement). (2021-04-21)
Subject	Medicine, Health and Life Sciences
Keyword	neglected disease, Trypanosoma brucei gambiense, parasitology, Point-of-Care Testing, diagnosis, African trypanosomiasis, Serologic tests
Notes	Manuscript submitted for publication. Data type: Survey data
License/Data Use Agreement	Custom Dataset Terms

Change View

Table

Tree

Filter by

	1 to 5 of 5 Files	Original Format Archival Format (.tab)
	DiTECT-HAT-WP2-CI-deidentified-2021-05-04.tab DiTECT-HAT/Tabular Data - 529.4 KB Published Jul 20, 2021 4 Downloads 50 Variables, 3433 Observations UNF:6:h9Cy8G5/SAO4IaPoWCW0zg== DiTECT-HAT-WP2 de-identified data (data dictionary: refer to DiTECT-HAT-WP2-CI-deidentified-2021-05-04 Metadata.docx) DataSurvey	Access File File Access Restricted Users may not request access to files. Download Metadata Data File Citation EndNote XML RIS BibTeX
	DiTECT-HAT-WP2-CI-deidentified-2021-05-04_Metadata.docx DiTECT-HAT/MS Word - 16.6 KB Published Jun 24, 2021 11 Downloads MD5: 87d5aea95e259fd0b98ef114ea9e7b00 DiTECT-HAT-WP2 Côte d'Ivoire metadata Documentation	Access File File Access Public Download Options MS Word Download Metadata Data File Citation EndNote XML RIS BibTeX
	DiTECT-HAT-WP2-ICF_AF-V1_1F-17-01-09.pdf DiTECT-HAT/Adobe PDF - 622.3 KB Published Jun 24, 2021 14 Downloads MD5: e6859745e7c41a5ae93828d3588cdf59 DiTECT-HAT-WP2 Informed consent form and ascent form Documentation	Access File File Access Public Download Options Adobe PDF Download Metadata Data File Citation EndNote XML RIS BibTeX
	DiTECT-HAT-WP2-Protocol-V1_2E-17-01-09.pdf DiTECT-HAT/Adobe PDF - 1.9 MB Published Jun 24, 2021 14 Downloads MD5: ff5e9506b784d9bdb8b63ca3809d5238 DiTECT-HAT-WP2 study protocol, English Documentation	Access File File Access Public Download Options Adobe PDF Download Metadata Data File Citation EndNote XML RIS BibTeX
	DiTECT-HAT-WP2-Protocol-V1_2F-17-01-09.pdf DiTECT-HAT/Adobe PDF - 2.2 MB Published Jun 24, 2021 13 Downloads MD5: b26bfac54b600072c0a232905b78aaac DiTECT-HAT-WP2 study protocol, French Documentation	Access File File Access Public Download Options Adobe PDF Download Metadata Data File Citation EndNote XML RIS BibTeX

Citation Metadata

Persistent Identifier	doi:10.23708/FNZDMZ
Publication Date	2021-06-24
Title	Passive case detection of Human African Trypanosomiasis in Côte d’Ivoire
Subtitle	DiTECT-HAT-WP2-Côte d'Ivoire
Alternative URL	https://www.clinicaltrials.gov/ct2/show/NCT03356665?term=DiTECT-HAT&draw=2&rank=2
Author	Lejon, Veerle (UMR INTERTRYP - IRD, CIRAD, Univ.Montpellier - France) - ORCID: 0000-0002-6795-0962 Kaba, Dramane (Institut Pierre Richet - Côte d'Ivoire) - ORCID: 0000-0001-7103-0440 Kabore, Jacques (CIRDES - Burkina Faso) Buscher, Philippe (Institute of Tropical Medicine - Belgium) - ORCID: 0000-0002-1926-7472 Kone, Minayégninrin (Institut Pierre Richet - Côte d'Ivoire) Kouame, Cyrille Mambo (Institut Pierre Richet - Côte d'Ivoire) Compaore, Charlie Franck Alfred (CIRDES - Burkina Faso) Jamonneau, Vincent (UMR INTERTRYP - IRD, CIRAD, Univ.Montpellier - France) - ORCID: 0000-0001-8427-0769
Point of Contact	Use email button above to contact. Lejon, Veerle (UMR INTERTRYP - IRD, CIRAD, Univ.Montpellier - France)
Description	In the last decade, the prevalence of Trypanosoma brucei gambiense human African trypanosomiasis (HAT) has fallen and HAT has been targeted for elimination. At low disease prevalence, integration of case finding into routine activities of peripheral health centres becomes crucial. However, HAT case detection by the peripheral health system with limited resources requires adapted diagnostic tests and test algorithms. The objective of the DiTECT-HAT-WP2 study was to determine the diagnostic performance and cost of rapid diagnostic tests (RDTs) performed on clinical suspects in peripheral health centres, whether or not followed by serological and/or molecular tests on filter paper done at regional reference centres. DiTECT-HAT has been registered in clinicaltrials.gov under ID NCT03356665, and is part of the DiTECT-HAT project, funded by EDCTP2-Horizon 2020- European Union. The DiTECT-HAT-WP2 study was conducted in centres for diagnosis and treatment and in sites for serological screening in Guinea, Côte d’Ivoire and DR Congo. In these centres and sites, clinical suspects were tested with several commercially available RDTs for HAT. Clinical suspects with at least 1 RDT positive result, 1° underwent parasitological examination and 2° blood collection on filter paper for reference analysis in trypanolysis, LAMP, ELISA and real-time PCR in the regional reference laboratory. If the reference laboratory tests and parasitological examinations were all negative, the suspect was considered free of HAT. If at least 1 reference test was positive, parasitological examinations were repeated at least twice at three months interval, unless trypanosomes were detected. The deposited file contains the DiTECT-HAT-WP2 study protocol in French and English, the informed consent form, and metadata of DiTECT-HAT-WP2 in Côte d'Ivoire. DiTECT-HAT-WP2 data will be made available to qualified researchers upon request after signing a confidentiality agreement. Data requests may be sent to the coordinating investigator (for coordinates see study protocol, Institut de Recherche pour le Développement). (2021-04-21)
Subject	Medicine, Health and Life Sciences
Keyword	neglected disease (Mesh) https://www.ncbi.nlm.nih.gov/mesh/68058069 Trypanosoma brucei gambiense (Mesh) https://www.ncbi.nlm.nih.gov/mesh/68014347 parasitology (Mesh) https://www.ncbi.nlm.nih.gov/mesh/68010274 Point-of-Care Testing (Mesh) https://www.ncbi.nlm.nih.gov/mesh/2009759 diagnosis (Mesh) https://www.ncbi.nlm.nih.gov/mesh/68003933 African trypanosomiasis (Mesh) https://www.ncbi.nlm.nih.gov/mesh/68014353 Serologic tests (Mesh) https://www.ncbi.nlm.nih.gov/mesh/68012698
Scientific Theme	Medical entomology, parasitology and virology (NumeriSud) https://uri.ird.fr/so/kos/tnu/052
Notes	Manuscript submitted for publication. Data type: Survey data
Language	English; French
Producer	Kaba, Dramane (Institut Pierre Richet) (IPR) https://iprci.org/ Lejon, Veerle (Institut de Recherche pour le Développement) (IRD) https://umr-intertryp.cirad.fr/
Production Date	2021-04-21
Production Location	Côte d'Ivoire
Contributor	Data Collector : Koné, Minayegninrin Data Manager : Büscher, Philippe Supervisor : Kaba, Dramane Work Package Leader : Kaboré, Jacques Data Collector : Kouamé, Cyrille Mambo Project Member : Compaoré, Charlie Franck Alfred Researcher : Jamonneau, Vincent Related Person : Koffi, Mathurin
Funding Information	EDCTP2: DRIA2014-306
Distributor	Lejon Veerle (IRD) (IRD) https://umr-intertryp.cirad.fr/
Depositor	Lejon, Veerle
Deposit Date	2021-04-21
Time Period	Start Date: 2017-08-01 ; End Date: 2020-12-31
Series	WP2, Côte d'Ivoire
Software	excel
Related Material	https://www.ditect-hat.eu/ https://publications.edctp.org/international-partnerships-against-infectious-diseases/ditec-hat https://www.clinicaltrials.gov/ct2/show/NCT03356665?term=DiTECT-HAT&draw=2&rank=2

Geospatial Metadata

Geographic Coverage	Côte d'Ivoire Bonon, Sinfra
Geographic Bounding Box	-6.241150139831007 -5.620422600768507 7.151766281372361 6.4945317524652

Dataset Terms

License/Data Use Agreement

Our Community Norms as well as good scientific practices expect that proper credit is given via citation. Please use the data citation shown on the dataset page.

Custom Dataset Terms — the following Custom Dataset Terms have been defined for this dataset.

This work is licensed under a Creative Commons Attribution 4.0 International License, except for the data file DiTECT-HAT-WP2-CI-deidentified-2021-05-04.tab

Ce(tte) œuvre est mise à disposition selon les termes de la Licence Creative Commons Attribution 4.0 International, à l'exception du fichier de données DiTECT-HAT-WP2-CI-deidentified-2021-05-04.tab

Restricted Files + Terms of Access

Restricted Files

There is 1 restricted file in this dataset.

Terms of Access for Restricted Files

Submit requests for data access to veerle.lejon@ird.fr

Request Access

Users may not request access to files.

	Dataset Version	Summary	Edited by	Published on
No records found.

Edit File

This file has already been deleted (or replaced) in the current version. It may not be edited.

Restrict Access

Restricting limits access to published files. People who want to use the restricted files can request access by default. If you disable request access, you must add information about access to the Terms of Access field.

Learn about restricting files and dataset access in the User Guide.

Request Access

Enable access request

You must enable request access or add terms of access to restrict file access.

Terms of Access for Restricted Files

Save Changes

Edit Embargo

The selected file or files have already been published. Contact an administrator to change the embargo date or reason of the file or files.

Delete Files

The file will be deleted after you click on the Delete button.

Files will not be removed from previously published versions of the dataset.

Select File(s)

Please select one or more files.

Share Dataset

Share this dataset on your favorite social media networks.

Dataset Citations

Citations for this dataset are retrieved from Crossref via DataCite using Make Data Count standards. For more information about dataset metrics, please refer to the User Guide.

Sorry, no citations were found.

Restricted Files Selected

The selected file(s) may not be downloaded because you have not been granted access.

Download Options

The files selected are too large to download as a ZIP.

You can select individual files that are below the 300.0 MB download limit from the files table, or use the Data Access API for programmatic access to the files.

Select File(s)

Please select a file or files to be downloaded.

Restricted Files Selected

The restricted file(s) selected may not be downloaded because you have not been granted access.

Click Continue to download the files you have access to download.

Delete Dataset

Are you sure you want to delete this dataset and all of its files? You cannot undelete this dataset.

Delete Draft Version

Are you sure you want to delete this draft version? Files will be reverted to the most recently published version. You cannot undelete this draft.

Unpublished Dataset Private URL

Private URL can only be used with unpublished versions of datasets.

Unpublished Dataset Private URL

Are you sure you want to disable the Private URL? If you have shared the Private URL with others they will no longer be able to use it to access your unpublished dataset.

Delete Files

The file(s) will be deleted after you click on the Delete button.

Files will not be removed from previously published versions of the dataset.

Compute

This dataset contains restricted files you may not compute on because you have not been granted access.

Deaccession Dataset

Are you sure you want to deaccession? The selected version(s) will no longer be viewable by the public.

Deaccession Dataset

Are you sure you want to deaccession this dataset? It will no longer be viewable by the public.

Version Differences Details

Please select two versions to view the differences.

Version Differences Details

Version:
Last Updated:

Select File(s)

Please select a file or files for access request.

Select File(s)

Embargoed files cannot be accessed. Please select an unembargoed file or files for your access request.

Edit Tags

Select existing file tags or create new tags to describe your files. Each file can have more than one tag.

Request Access

You need to Log In to request access.

Dataset Terms

This dataset is made available under the following terms. Please confirm and/or complete the information needed below in order to continue.

License/Data Use Agreement

Our Community Norms as well as good scientific practices expect that proper credit is given via citation. Please use the data citation shown on the dataset page.

Custom terms specific to this dataset Custom Dataset Terms — the following Custom Dataset Terms have been defined for this dataset.

This work is licensed under a Creative Commons Attribution 4.0 International License, except for the data file DiTECT-HAT-WP2-CI-deidentified-2021-05-04.tab

Preview Guestbook

Upon downloading files the guestbook asks for the following information.

Guestbook Name

Collected Data

Account Information

Package File Download

Use the Download URL in a Wget command or a download manager to download this package file. Download via web browser is not recommended. User Guide - Downloading a Dataverse Package via URL

Download URL

https://dataverse.ird.fr/api/access/datafile/

Request Access

Please confirm and/or complete the information needed below in order to request access to files in this dataset.

Terms of Access for Restricted Files

Submit requests for data access to veerle.lejon@ird.fr

Compute Batch

Clear Batch

Dataset	Persistent Identifier	Change Compute Batch

Compute Batch

Submit for Review

You will not be able to make changes to this dataset while it is in review.

Publish Dataset

Are you sure you want to republish this dataset?

Select if this is a minor or major version update.

Minor Release (2.2)

Major Release (3.0)

Publish Dataset

This dataset cannot be published until DiTECT-HAT-WP2 is published by its administrator.

Publish Dataset

This dataset cannot be published until DiTECT-HAT-WP2 and DiTECT-HAT are published.

Return to Author

Return this dataset to contributor for modification.