Protocol, Replication Data and Codes for: Non-pyrethroid indoor residual spraying or intensive behavior change communication in combination with long-lasting insecticidal nets against malaria disease in West Africa: a pragmatic transnational cluster-randomized controlled trial.

Version 2.0

Moiroux, Nicolas; Taconet, Paul; Soma, Diloma Dieudonné; Zogo, Barnabas, 2025, "Protocol, Replication Data and Codes for: Non-pyrethroid indoor residual spraying or intensive behavior change communication in combination with long-lasting insecticidal nets against malaria disease in West Africa: a pragmatic transnational cluster-randomized controlled trial.", https://doi.org/10.23708/MZ7KZZ, DataSuds, V2

Learn about Data Citation Standards.

Contact Owner

Dataset Metrics

7 Downloads

Description	This repository contains the protocol, the data and analyses scripts for a Randomized Controlled Trial evaluating Indoor Residual Spraying (IRS) or Behavioral Change Communication in combination to Long-Lasting Insecticidal Nets (LLIN) in Burkina Faso (BF) and Côte d'Ivoire (CI). A detailed description of the dataset organization and content is provided in the 'README.md' file. (2025-06-02)
Subject	Medicine, Health and Life Sciences
Keyword	Malaria, Randomized Controlled Trial, Insecticide-Treated Bednets, Health Communication, Insecticide Resistance
Related Publication	Moiroux N, Zongo I, Assi S-B, et al. Efficacy of non-pyrethroid indoor residual spraying or intensive behaviour change communication in combination with long-lasting insecticidal nets for malaria control in west Africa: a pragmatic, cluster-randomised, controlled trial. The Lancet Global Health 2025; 13: e1605–16. doi: 10.1016/s2214-109x(25)00216-5
Notes	Data Type : Analysis Data and source code
License/Data Use Agreement	Custom Dataset Terms

Change View

Table

Tree

Filter by

	1 to 10 of 23 Files	Download Request Access
	DataUseAgreement_doi_10_23708_MZ7KZZ.docx MS Word - 30.9 KB Published Aug 29, 2025 0 Downloads MD5: 7136ff2ae8d340d6475a24cc1a832576 Data use agreement form. The form must be downloaded, completed and returned to the authors of the dataset and data@ird.fr before access to the data files is granted. Documentation	Access File File Access Public Download Options MS Word Download Metadata Data File Citation EndNote XML RIS BibTeX
	README.md Markdown Text - 6.6 KB Published Aug 29, 2025 1 Download MD5: 40abab81083cc9231ff8d012d4126515 Read first. Repository description. Analysis files (R codes) description. Documentation	Preview "README.md" Access File File Access Public Download Options Markdown Text Download Metadata Data File Citation EndNote XML RIS BibTeX
	ReadMe_FYYQHFP.txt Plain Text - 1.7 KB Published Aug 29, 2025 1 Download MD5: e70f2153ac092abc440bcc69df9b978b Contains citation, description and conditions of use of dataset data Documentation	Preview "ReadMe_FYYQHFP.txt" Access File File Access Public Download Options Plain Text Download Metadata Data File Citation EndNote XML RIS BibTeX
	data.RData Data/Gzip Archive - 388.7 KB Published Aug 29, 2025 0 Downloads MD5: 9638301e1fa3a9a060e0cda7dd732ab5 Data for epidemiological outcomes analysis Données	Access File File Access Restricted Request Access Download Metadata Data File Citation EndNote XML RIS BibTeX
	data2.RData Data/R Data - 138.9 KB Published Aug 29, 2025 0 Downloads MD5: 3ac5c0bc8a845fa37f5c167e3cdc0d62 Data for bednet use analysis Données	Access File File Access Restricted Request Access Download Metadata Data File Citation EndNote XML RIS BibTeX
	data_meta_IRS.RData Data/R Data - 508 B Published Aug 29, 2025 0 Downloads MD5: df779d1ee46a215bc6bf44e93d3f7a12 Data for Non-Pyrethroid IRS meta-analysis Données	Access File File Access Public Download Options R Data Download Metadata Data File Citation EndNote XML RIS BibTeX
	entomo.RData Data/Gzip Archive - 1.1 MB Published Aug 29, 2025 0 Downloads MD5: fff476414054a3c97da8eedbd5bd719e Data for entomological outcomes analysis Données	Access File File Access Public Download Options Gzip Archive Download Metadata Data File Citation EndNote XML RIS BibTeX
	metadata.Rmd Documentation/R Notebook - 32.1 KB Published Aug 29, 2025 0 Downloads MD5: 99fa159a6d38c2f70432506d86216d14 R Markdown file of metadata and dataset descriptions (data dictionnary) Documentation	Access File File Access Public Download Options R Notebook Download Metadata Data File Citation EndNote XML RIS BibTeX
	REACT_protocol.pdf Documentation/Adobe PDF - 138.3 KB Published Aug 29, 2025 3 Downloads MD5: cc9380a40110fc76cd1c22fdfa110976 This is the protocol of the REACT trial. Documentation	Preview "Documentation/REACT_protocol.pdf" Access File File Access Public Download Options Adobe PDF Download Metadata Data File Citation EndNote XML RIS BibTeX
	Meta_analysis_nonPYR_IRS_update.R R/R Syntax - 1007 B Published Aug 29, 2025 0 Downloads MD5: 020d85637740ee21ad149098badd4dae Analysis code: see README.md Code	Preview "R/Meta_analysis_nonPYR_IRS_update.R" Access File File Access Public Download Options R Syntax Download Metadata Data File Citation EndNote XML RIS BibTeX

Citation Metadata

Persistent Identifier	doi:10.23708/MZ7KZZ
Publication Date	2025-08-29
Title	Protocol, Replication Data and Codes for: Non-pyrethroid indoor residual spraying or intensive behavior change communication in combination with long-lasting insecticidal nets against malaria disease in West Africa: a pragmatic transnational cluster-randomized controlled trial.
Alternative URL	https://github.com/Nmoiroux/REACT_TLGH
Author	Moiroux, Nicolas (UMR MIVEGEC - IRD, CNRS, Univ.Montpellier - France) - ORCID: 0000-0001-6755-6167 Taconet, Paul (UMR MIVEGEC - IRD, CNRS, Univ.Montpellier - France) - ORCID: 0000-0001-7429-7204 Soma, Diloma Dieudonné (Institut de Recherche en Sciences de la Santé - Burkina Faso) - ORCID: 0000-0003-2717-6359 Zogo, Barnabas (Institut Pierre Richet - Côte d'Ivoire) - ORCID: 0000-0002-9622-1339
Point of Contact	Use email button above to contact. MOIROUX, Nicolas (UMR MIVEGEC - IRD, CNRS, Univ.Montpellier - France)
Description	This repository contains the protocol, the data and analyses scripts for a Randomized Controlled Trial evaluating Indoor Residual Spraying (IRS) or Behavioral Change Communication in combination to Long-Lasting Insecticidal Nets (LLIN) in Burkina Faso (BF) and Côte d'Ivoire (CI). A detailed description of the dataset organization and content is provided in the 'README.md' file. (2025-06-02)
Subject	Medicine, Health and Life Sciences
Keyword	Malaria (MeSH) https://id.nlm.nih.gov/mesh/D008288.html Randomized Controlled Trial (MeSH) https://id.nlm.nih.gov/mesh/D016449.html Insecticide-Treated Bednets (MeSH) https://id.nlm.nih.gov/mesh/D057148.html Health Communication (MeSH) https://id.nlm.nih.gov/mesh/D058015.html Insecticide Resistance (MeSH) https://id.nlm.nih.gov/mesh/D007305.html
Scientific Theme	Medical entomology, parasitology and virology (NumeriSud) https://uri.ird.fr/so/kos/tnu/052
Related Publication	Moiroux N, Zongo I, Assi S-B, et al. Efficacy of non-pyrethroid indoor residual spraying or intensive behaviour change communication in combination with long-lasting insecticidal nets for malaria control in west Africa: a pragmatic, cluster-randomised, controlled trial. The Lancet Global Health 2025; 13: e1605–16. doi: 10.1016/s2214-109x(25)00216-5 https://doi.org/10.1016/s2214-109x(25)00216-5
Notes	Data Type : Analysis Data and source code
Language	English
Contributor	Project Leader : Moiroux, Nicolas Project Leader : Pennetier, Cedric Project Leader : Koffi, Alphonsine Project Leader : Dabire, Roch K. Researcher : Zongo, Issaka Researcher : Assi, Serge-Brice Researcher : Mouline, Karine Data Collector : Somé, Anthony Data Collector : Tchiekoi, Bertin N'cho Data Collector : Soma, Diloma Dieudonné Data Collector : Zogo, Barnabas Data Manager : Taconet, Paul Researcher : Taconet, Paul Hosting Institution : IRSS - Institut de Recherche en Sciences de la Santé - Bobo-Dioulasso Hosting Institution : IPR - Institut Pierre Richet - Bouaké
Funding Information	Expertise France - L'Initiative: 15SANIN213
Depositor	MOIROUX, Nicolas
Deposit Date	2025-06-02
Time Period	Start Date: 2016-07-01 ; End Date: 2018-08-31
Related Material	Zogo, Barnabas, Dieudonné Diloma Soma, Bertin N’Cho Tchiekoi, Anthony Somé, Ludovic P. Ahoua Alou, Alphonsine A. Koffi, Florence Fournet, et al. ‘Anopheles Bionomics, Insecticide Resistance Mechanisms, and Malaria Transmission in the Korhogo Area, Northern Côte d’Ivoire: A Pre-Intervention Study’. Parasite 26 (2019): 40. https://doi.org/10.1051/parasite/2019040 ; Soma, Dieudonné Diloma, Barnabas Mahugnon Zogo, Anthony Somé, Bertin N’Cho Tchiekoi, Domonbabele François de Sales Hien, Hermann Sié Pooda, Sanata Coulibaly, et al. ‘Anopheles Bionomics, Insecticide Resistance and Malaria Transmission in Southwest Burkina Faso: A Pre-Intervention Study’. PLoS ONE 15, no. 8 (3 August 2020). https://doi.org/10.1371/journal.pone.0236920 ; Bationo, Cédric S., Jean Gaudart, Sokhna Dieng, Mady Cissoko, Paul Taconet, Boukary Ouedraogo, Anthony Somé, et al. ‘Spatio-Temporal Analysis and Prediction of Malaria Cases Using Remote Sensing Meteorological Data in Diébougou Health District, Burkina Faso, 2016-2017’. Scientific Reports 11, no. 1 (8 October 2021): 20027. https://doi.org/10.1038/s41598-021-99457-9 ; Soma, D. D., B. Zogo, P. Taconet, A. Somé, S. Coulibaly, L. Baba-Moussa, G. A. Ouédraogo, et al. ‘Quantifying and Characterizing Hourly Human Exposure to Malaria Vectors Bites to Address Residual Malaria Transmission during Dry and Rainy Seasons in Rural Southwest Burkina Faso’. BMC Public Health 21, no. 1 (30 January 2021): 251. https://doi.org/10.1186/s12889-021-10304-y ; Soma, Dieudonné Diloma, Barnabas Zogo, Domonbabele François de Sales Hien, Aristide Sawdetuo Hien, Didier Alexandre Kaboré, Mahamadi Kientega, Anicet Georges Ouédraogo, et al. ‘Insecticide Resistance Status of Malaria Vectors Anopheles Gambiae (s.l.) of Southwest Burkina Faso and Residual Efficacy of Indoor Residual Spraying with Microencapsulated Pirimiphos-Methyl Insecticide’. Parasites & Vectors 14, no. 1 (18 January 2021): 58. https://doi.org/10.1186/s13071-020-04563-8 ; Taconet, Paul, Angélique Porciani, Dieudonné Diloma Soma, Karine Mouline, Frédéric Simard, Alphonsine Amanan Koffi, Cedric Pennetier, Roch Kounbobr Dabiré, Morgan Mangeas, and Nicolas Moiroux. ‘Data-Driven and Interpretable Machine-Learning Modeling to Explore the Fine-Scale Environmental Determinants of Malaria Vectors Biting Rates in Rural Burkina Faso’. Parasites & Vectors 14, no. 1 (29 June 2021): 345. https://doi.org/10.1186/s13071-021-04851-x ; Taconet, Paul, Barnabas Zogo, Dieudonné Diloma Soma, Ludovic P. Ahoua Alou, Karine Mouline, Roch Kounbobr Dabiré, Alphonsine Amanan Koffi, Cédric Pennetier, and Nicolas Moiroux. ‘Anopheles Sampling Collections in the Health Districts of Korhogo (Côte d’Ivoire) and Diébougou (Burkina Faso) between 2016 and 2018’. Gigabyte 2023 (30 June 2023): 1–10. https://doi.org/10.46471/gigabyte.83 ; Taconet, Paul, Dieudonné Diloma Soma, Barnabas Zogo, Karine Mouline, Frédéric Simard, Alphonsine Amanan Koffi, Roch Kounbobr Dabiré, Cédric Pennetier, and Nicolas Moiroux. ‘Physiological and behavioural resistance of malaria vectors in rural West-Africa: a data mining study to address their fine-scale spatiotemporal heterogeneity, drivers, and predictability’. Peer Community Journal 4 (2024). https://doi.org/10.24072/pcjournal.367 ; Taconet, Paul, Barnabas Zogo, Ludovic P. Ahoua Alou, Alphonsine Amanan Koffi, Roch Kounbobr Dabiré, Cedric Pennetier, and Nicolas Moiroux. ‘Landscape and Meteorological Determinants of Malaria Vectors’ Presence and Abundance in the Rural Health District of Korhogo, Côte d’Ivoire, 2016–2018, and Comparison with the Less Anthropized Area of Diébougou, Burkina Faso’. PLOS ONE 19, no. 10 (21 October 2024): e0312132. https://doi.org/10.1371/journal.pone.0312132
Related Dataset	Soma, Dieudonné Diloma, Barnabas Zogo, Paul Taconet, Karine Mouline, Ludovic P. Ahoua Alou, Roch Kounbobr Dabiré, Alphonsine Amanan Koffi, Cédric Pennetier, and Nicolas Moiroux. ‘Anopheles Collections in the Health Districts of Korhogo (Côte d’Ivoire) and Diébougou (Burkina Faso) (2016-2018)’, 2023. https://doi.org/10.15468/v8fvyn ; Moiroux, Nicolas, Cédric Pennetier, Roch Kounbobr Dabiré, and Alphonsine Koffi. ‘REACT Project (Burkina Faso and Côte d’Ivoire, 2016-2018): Study Sites Information’. DataSuds, 4 December 2023. https://doi.org/10.23708/IX5Z7U

Geospatial Metadata

Geographic Coverage	Burkina Faso Sud-Ouest Diébougou Côte d'Ivoire Savanes District Korhogo
Geographic Bounding Box	-3.7985229492187504 -3.0844116210937504 11.108337084308143 10.350045832740452 -5.861206054687501 -5.155334472656251 9.73612839582732 8.90678000752024

Dataset Terms

License/Data Use Agreement

Our Community Norms as well as good scientific practices expect that proper credit is given via citation. Please use the data citation shown on the dataset page.

Custom Dataset Terms — the following Custom Dataset Terms have been defined for this dataset.

Documentation files and free data file download

This work is licensed under a Creative Commons Attribution 4.0 International License.

Fichiers de documentation et fichiers de données en accès libre

Ce(tte) œuvre est mise à disposition selon les termes de la Licence Creative Commons Attribution 4.0 International.

Authorized access data file
Restricted access subject to author consent as defined in the “DataUseAgreement” document to be filled in and signed.

Fichier de données en accès avec autorisation
Accès restreint et soumis à accord des auteurs tel que défini dans le document "DataUseAgreement" à remplir et signer

Restricted Files + Terms of Access

Restricted Files

There are 2 restricted files in this dataset.

Terms of Access for Restricted Files

This data set is sensitive because it contains pseudonymized personal health data. Any attempt to re-identify participants is strictly forbidden. Data are available on request from the authors by filling in and sending the “DataUseAgreement_doi_10_23708_MZ7KZZ.docx” form along with the dataset files, with a copy to DataSuds (data@ird.fr). Access to the data is subject to approval and a data-sharing agreement. This dataset may only be used for scientific research purposes, directly related to the project cited in the request for use.

Cet ensemble de données est sensible car il contient des données de santé personnelles pseudonymisées. Toute tentative de ré-identification des participants est strictement interdite. Les données sont disponibles sur demande auprès des auteurs en remplissant et en envoyant le formulaire « DataUseAgreement_doi_10_23708_MZ7KZZ.docx » disponible avec les fichiers de l'ensemble de données, avec une copie à DataSuds (data@ird.fr). L'accès aux données est soumis à une approbation et à un accord de partage des données. Cet ensemble de données ne peut être utilisé qu'à des fins de recherche scientifique, directement liées au projet cité dans la demande d'utilisation.

Request Access

Users may request access to files.

Dataset Version	Summary	Edited by	Published on
No records found.

Edit File

This file has already been deleted (or replaced) in the current version. It may not be edited.

Restrict Access

Restricting limits access to published files. People who want to use the restricted files can request access by default. If you disable request access, you must add information about access to the Terms of Access field.

Learn about restricting files and dataset access in the User Guide.

Request Access

Enable access request

You must enable request access or add terms of access to restrict file access.

Terms of Access for Restricted Files

Save Changes

Edit Embargo

The selected file or files have already been published. Contact an administrator to change the embargo date or reason of the file or files.

Delete Files

The file will be deleted after you click on the Delete button.

Files will not be removed from previously published versions of the dataset.

Select File(s)

Please select one or more files.

Share Dataset

Share this dataset on your favorite social media networks.

Continue

Dataset Citations

Citations for this dataset are retrieved from Crossref via DataCite using Make Data Count standards. For more information about dataset metrics, please refer to the User Guide.

Sorry, no citations were found.

Restricted Files Selected

The selected file(s) may not be downloaded because you have not been granted access.

You may request access to the restricted file(s) by clicking the Request Access button.

Download Options

The files selected are too large to download as a ZIP.

You can select individual files that are below the 300.0 MB download limit from the files table, or use the Data Access API for programmatic access to the files.

Select File(s)

Please select a file or files to be downloaded.

Restricted Files Selected

The restricted file(s) selected may not be downloaded because you have not been granted access.

Click Continue to download the files you have access to download.

Ineligible Files Selected

Some file(s) cannot be transferred. (They are restricted, embargoed, or not Globus accessible.)

Click Continue to transfer the elligible files.

Delete Dataset

Are you sure you want to delete this dataset and all of its files? You cannot undelete this dataset.

Delete Draft Version

Are you sure you want to delete this draft version? Files will be reverted to the most recently published version. You cannot undelete this draft.

Unpublished Dataset Private URL

Private URL can only be used with unpublished versions of datasets.

Unpublished Dataset Private URL

Are you sure you want to disable the Private URL? If you have shared the Private URL with others they will no longer be able to use it to access your unpublished dataset.

Delete Files

The file(s) will be deleted after you click on the Delete button.

Files will not be removed from previously published versions of the dataset.

Compute

This dataset contains restricted files you may not compute on because you have not been granted access.

Deaccession Dataset

Are you sure you want to deaccession? This is permanent and the selected version(s) will no longer be viewable by the public.

Deaccession Dataset

Are you sure you want to deaccession this dataset? This is permanent an it will no longer be viewable by the public.

Version Differences Details

Please select two versions to view the differences.

Version Differences Details

Version:
Last Updated:

Select File(s)

Please select a file or files for access request.

Select File(s)

Embargoed files cannot be accessed. Please select an unembargoed file or files for your access request.

Edit Tags

Select existing file tags or create new tags to describe your files. Each file can have more than one tag.

Request Access

You need to Log In to request access.

Dataset Terms

Please confirm and/or complete the information needed below in order to request access to files in this dataset.

This dataset is made available under the following terms. Please confirm and/or complete the information needed below in order to continue.

License/Data Use Agreement

Our Community Norms as well as good scientific practices expect that proper credit is given via citation. Please use the data citation shown on the dataset page.

Custom terms specific to this dataset Custom Dataset Terms — the following Custom Dataset Terms have been defined for this dataset.

This work is licensed under a Creative Commons Attribution 4.0 International License.

Fichiers de documentation et fichiers de données en accès libre

Ce(tte) œuvre est mise à disposition selon les termes de la Licence Creative Commons Attribution 4.0 International.

Authorized access data file
Restricted access subject to author consent as defined in the “DataUseAgreement” document to be filled in and signed.

Fichier de données en accès avec autorisation
Accès restreint et soumis à accord des auteurs tel que défini dans le document "DataUseAgreement" à remplir et signer

Name

Institution

Position

Preview Guestbook

Upon downloading files the guestbook asks for the following information.

Guestbook Name

Collected Data

Account Information

Package File Download

Use the Download URL in a Wget command or a download manager to download this package file. Download via web browser is not recommended. User Guide - Downloading a Dataverse Package via URL

Download URL

https://dataverse.ird.fr/api/access/datafile/

Compute Batch

Clear Batch

Dataset	Persistent Identifier	Change Compute Batch

Compute Batch

Submit for Review

You will not be able to make changes to this dataset while it is in review.

Publish Dataset

Are you sure you want to republish this dataset?

Select if this is a minor or major version update.

Minor Release (2.1)

Major Release (3.0)

Publish Dataset

This dataset cannot be published until REACT Project is published by its administrator.

Publish Dataset

This dataset cannot be published until REACT Project and UMR MIVEGEC are published.

Return to Author

Return this dataset to contributor for modification. The reason for return entered below will be sent by email to the author.