Replication data for : Loa loa microfilaremia and dementia: a community-based cross-sectional study in southern Cameroon.

Version 1.0
Replication data for : Loa loa microfilaremia and dementia: a community-based cross-sectional study in southern Cameroon.
Campillo, Jeremy; Checkouri, Thomas; Kongnyu Gamnsi Njamnshi; Elsie Linda Petchou-Talla; Achille Francklin Djomou Nzessu; Olivia Portalier; Nadia Nga-Elomo; Sébastien D. S. Pion; Bachiratou Sahm; Tristan M. Lepage; Guy S. Wafeu; Michel Boussinesq; Alfred K. Njamnshi; Cédric B. Chesnais, 2026, "Replication data for : Loa loa microfilaremia and dementia: a community-based cross-sectional study in southern Cameroon.", https://doi.org/10.23708/IJDPMR, DataSuds, V1, UNF:6:N3EQq5hiH4M7FILuVlSJFA== [fileUNF]
Learn about Data Citation Standards.
Dataset Metrics
0 Downloads
Description
The data originate from the present DELOCAM study, conducted in Cameroon among an adult population, as an extension of a research programme dedicated to the neurological morbidity of loiasis. They were assembled to jointly characterise, within the same individual, cognitive and functional status, exposure to chronic parasitic infections, and the associated cardiovascular, renal, and sociodemographic markers.
This data collection addresses the near-complete absence of individual-level data linking parasitic exposure and cognitive ageing in a region where these infections are nonetheless highly prevalent.

The acquisition aimed to estimate the frequency of cognitive impairment and dementia, and then to examine their association with filarial exposure — in particular Loa loa microfilaraemia — with other helminthiases, with markers of arterial stiffness and subclinical atherosclerosis (PWV, IMT), and with cardiometabolic risk factors. It further aimed to produce an individual-level dataset — structured, standardised, and reusable — combining, within the same population, quantitative parasitological phenotyping, domain-specific cognitive assessment, and cardiovascular characterisation.
The value of this dataset lies in the rarity of the combination it documents within a single Central African population: microfilarial densities and helminthic positivity, domain-specific cognitive scores, and composite indices. It supports secondary analyses, integration into regional meta-analyses, and methodological work on the adaptation of cognitive and functional-autonomy instruments to this setting.

Brief Abstract of the associated publication: Checkouri et al. report that higher Loa loa microfilarial blood density is associated with greater odds of cognitive impairment and dementia in a community-based cross-sectional study in southern Cameroon, identifying chronic filarial infection as a candidate, previously overlooked contributor to cognitive decline in rural Central Africa. (2026-06-25)
Subject Medicine, Health and Life Sciences
Keyword loiasis, cognition, dementia
Related Publication Submitted.

Loa loa microfilaremia and dementia: a community-based cross-sectional study in the South Region of Cameroon Short title: Loa loa–associated neurocognitive disorders Thomas Checkouri1,2 (MD, MsC), Kongnyu Gamnsi Njamnshi (MD)3,4, Elsie Linda Petchou-Talla (MD) 3,4, Achille Francklin Djomou Nzessu (MD)3,4, Olivia Portalier (MSc)1, Nadia Nga-Elomo (MsC)5, Sébastien D. S. Pion (PhD)5, Bachiratou Sahm (MSc)5, Tristan M. Lepage (MD)5, Guy S. Wafeu (MD, PhD) 5,6, Michel Boussinesq (MD, PhD) 5, Alfred K. Njamnshi (MD, MA)3,4, Cédric B. Chesnais (MD, PhD) 5,7, Jeremy T. Campillo (PharmD, PhD)5 1 Neuroradiology department, Montpellier University Hospital, Gui de Chauliac, Montpellier, France 2 Institute of Functional Genomics, University of Montpellier, CNRS, INSERM, Montpellier, France 3 Brain Research Africa Initiative (BRAIN), Yaoundé P.O. Box 25625, Cameroon and 1226 Geneva, Switzerland. 4 Neuroscience Lab, Faculty of Medicine and Biomedical Sciences, The University of Yaoundé I, Yaoundé P.O. Box 1364, Cameroon. 5 TransVIHMI, Université de Montpellier, INSERM Unité 1175, Institut de Recherche pour le Développement (IRD), Montpellier, France. 6 Higher Institute for Scientific and Medical Research (ISM), Yaoundé, Cameroon. 7 Programme National de Lutte contre l'Onchocercose, Direction de l'Épidémiologie et de la Lutte contre la Maladie, Ministère de la Santé et de la Population, Brazzaville, Republic of the Congo.
License/Data Use Agreement

Custom Dataset Terms

Table
Tree
Filter by
1 to 5 of 5 Files
 Request Access
Data_Use_Agreement_doi_10_23708_IJDPMR.docx
MS Word - 13.3 KB
Published Jul 6, 2026
0 Downloads
MD5: 2310b6f16fd110d67c4051f3da3f42aa
Form for requesting access to restricted data. This form must be downloaded, completed, signed and sent to the contact point for this dataset and to data@ird.fr for any request for access to restricted data as described in the terms of use.
Documentation
ReadMe_10-23708_IJDPMR.txt
Plain Text - 4.0 KB
Published Jul 6, 2026
0 Downloads
MD5: ccea43c2547a06c32ac21927fcd50b5b
contains the citation, description and conditions of use, or even access, depending on the case, to the dataset
Documentation
Preview "ReadMe_10-23708_IJDPMR.txt"
BNP_Analysis.do
data_and_metadata/Stata Syntax - 22.0 KB
Published Jul 6, 2026
0 Downloads
MD5: 92b3ef27c9f389b0f0ab477389883ea1
Analysis script – .do format (Stata)
Code
BNP_CMR_Brain_data.tab
data_and_metadata/Tabular Data - 50.1 KB
Published Jul 6, 2026
0 Downloads
32 Variables, 267 Observations UNF:6:N3EQq5hiH4M7FILuVlSJFA==
Pseudo-anonymised database and variable dictionary
Données
Protocole_21-03-24_DELOCAM.pdf
Protocole_21-03-24_DELOCAM.pdf
data_and_metadata/Adobe PDF - 195.3 KB
Published Jul 6, 2026
0 Downloads
MD5: 0a165b446d053c1acab92480465975ad
research protocol
Documentation
Preview "data_and_metadata/Protocole_21-03-24_DELOCAM.pdf"
Edit File

This file has already been deleted (or replaced) in the current version. It may not be edited.

Restrict Access

Restricting limits access to published files. People who want to use the restricted files can request access by default. If you disable request access, you must add information about access to the Terms of Access field.

Learn about restricting files and dataset access in the User Guide.

Enable access request
You must enable request access or add terms of access to restrict file access.
Save Changes
Edit Embargo

The selected file or files have already been published. Contact an administrator to change the embargo date or reason of the file or files.
Delete Files

The file will be deleted after you click on the Delete button.

Files will not be removed from previously published versions of the dataset.

Select File(s)

Please select one or more files.

Share Dataset

Share this dataset on your favorite social media networks.

Continue
Dataset Citations

Citations for this dataset are retrieved from Crossref via DataCite using Make Data Count standards. For more information about dataset metrics, please refer to the User Guide.

Sorry, no citations were found.
Restricted Files Selected

The selected file(s) may not be downloaded because you have not been granted access.

You may request access to the restricted file(s) by clicking the Request Access button.

Download Options

The files selected are too large to download as a ZIP.

You can select individual files that are below the 300.0 MB download limit from the files table, or use the Data Access API for programmatic access to the files.

Select File(s)

Please select a file or files to be downloaded.

Restricted Files Selected

The restricted file(s) selected may not be downloaded because you have not been granted access.

Click Continue to download the files you have access to download.

Ineligible Files Selected

Some file(s) cannot be transferred. (They are restricted, embargoed, or not Globus accessible.)

Click Continue to transfer the elligible files.

Delete Dataset

Are you sure you want to delete this dataset and all of its files? You cannot undelete this dataset.

Delete Draft Version

Are you sure you want to delete this draft version? Files will be reverted to the most recently published version. You cannot undelete this draft.

Unpublished Dataset Private URL

Private URL can only be used with unpublished versions of datasets.

Unpublished Dataset Private URL

Are you sure you want to disable the Private URL? If you have shared the Private URL with others they will no longer be able to use it to access your unpublished dataset.

Delete Files

The file(s) will be deleted after you click on the Delete button.

Files will not be removed from previously published versions of the dataset.

Compute

This dataset contains restricted files you may not compute on because you have not been granted access.

Deaccession Dataset

Are you sure you want to deaccession? This is permanent and the selected version(s) will no longer be viewable by the public.

Deaccession Dataset

Are you sure you want to deaccession this dataset? This is permanent an it will no longer be viewable by the public.

Version Differences Details

Please select two versions to view the differences.

Version Differences Details
 
Version:
Last Updated:
Version:
Last Updated:
Select File(s)

Please select a file or files for access request.

Select File(s)

Embargoed files cannot be accessed. Please select an unembargoed file or files for your access request.

Edit Tags

Select existing file tags or create new tags to describe your files. Each file can have more than one tag.

Request Access

  You need to Log In to request access.

Dataset Terms

Please confirm and/or complete the information needed below in order to request access to files in this dataset.

This dataset is made available under the following terms. Please confirm and/or complete the information needed below in order to continue.

Our Community Norms as well as good scientific practices expect that proper credit is given via citation. Please use the data citation shown on the dataset page.

Custom Dataset Terms — the following Custom Dataset Terms have been defined for this dataset.

Documentation files
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Fichiers de documentation
Licence Creative Commons
Ce(tte) œuvre est mise à disposition selon les termes de la Licence Creative Commons Attribution 4.0 International.
Authorized access data file
This dataset is sensitive as it contains pseudonymised data. Any attempt to re-identify participants is strictly prohibited. This dataset may only be used for scientific research purposes and in accordance with the conditions set out in the DataUseAgreement form, as mentioned in the ‘Access Conditions’ section below.
Fichier de données en accès avec autorisation
Cet ensemble de données est sensible car il contient des données pseudonymisées. Toute tentative de réidentification des participants est strictement interdite. Cet ensemble de données ne peut être utilisé qu'à des fins de recherches scientifiques et dans les conditions définies au sein du formulaire DataUseAgreement, comme mentionné dans la catégorie "Conditions d'accès" ci-après.
Preview Guestbook

Upon downloading files the guestbook asks for the following information.

Account Information

Package File Download

Use the Download URL in a Wget command or a download manager to download this package file. Download via web browser is not recommended. User Guide - Downloading a Dataverse Package via URL

https://dataverse.ird.fr/api/access/datafile/

Compute Batch
Clear Batch
Dataset Persistent Identifier Change Compute Batch
Compute Batch
Submit for Review

You will not be able to make changes to this dataset while it is in review.

Publish Dataset

Are you sure you want to republish this dataset?

Select if this is a minor or major version update.

Publish Dataset

This dataset cannot be published until UMI TransVIHMI is published by its administrator.

Publish Dataset

This dataset cannot be published until UMI TransVIHMI and DataSuds are published.

Return to Author

Return this dataset to contributor for modification. The reason for return entered below will be sent by email to the author.