Unité Mixte Internationale TransVIHMI

L’UMI 233 étudie principalement les spécificités de l’infection par le VIH au Sud et ses conséquences pour les populations. L’impact du VIH sur les autres endémies infectieuses tropicales fait que le champ des recherches aborde aussi la problématique des co-infections (hépatites, tuberculose) et d’autres maladies tropicales négligées telles que les filarioses et plus récemment l'infection par le virus Ebola. Autour de cette unité thématique, et cela depuis sa création il y a près de 20 ans, l’UMI 233 mène des travaux de recherches transversales pluridisciplinaires associant virologie, parasitologie, clinique, épidémiologie, santé publique et sciences sociales. Si le VIH et les Maladies Associées restent le thème principal de l'unité, l'unité mène des travaux sur les Maladies Tropicales Négligées comme la filariose, l'infection par le virus Ebola et tout récemment l’infection par le virus SARS-CoV-2 .
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21 to 30 of 72 Results
WHODAS_Loa_Congo_PlosNTD_Dictionnary_Data.tab
May 23, 2025 - Disability and quality of life assessment using WHODAS-12 items 2.0 and EQ-5D-5L in a rural area endemic for loiasis in the Republic of Congo: a population-based cross-sectional study (the MorLo project)
Tabular Data - 2.5 KB - 12 Variables, 36 Observations - UNF:6:ui7L6W5QiM700BJWaUsesg==
Documentation
Data dictionnary
Replication data for Safety and efficacy of 3- and 5-day regimens of levamisole in loiasis: a randomized, placebo-controlled, double-blind clinical trial
May 23, 2025
Cédric B. Chesnais; Marlhand C. Hemilembolo; Bachiratou A. Sahm; Florentin Toutin; Ericson Djeutassong; Nadia Nga-Elomo; Benjamin Cuer; Mas A. Ntsiba-N’goulou; Miveck Pakat; Sébastien D. S. Pion; François Missamou; Michel Boussinesq; Jérémy T Campillo, 2025, "Replication data for Safety and efficacy of 3- and 5-day regimens of levamisole in loiasis: a randomized, placebo-controlled, double-blind clinical trial", https://doi.org/10.23708/TTJXSF, DataSuds, V1, UNF:6:QDTu5z2Y7xIeanRSu3mpUw== [fileUNF]
Background. Individuals with high Loa loa microfilarial densities (MFD) risk serious adverse events (SAEs) following ivermectin treatment. A single dose of levamisole (LEV) induces a temporary, progressive MFD decrease. We assessed the safety and efficacy of 3- and 5-day LEV (LEV...
CRF.pdf
May 23, 2025 - Replication data for Safety and efficacy of 3- and 5-day regimens of levamisole in loiasis: a randomized, placebo-controlled, double-blind clinical trial
Adobe PDF - 879.3 KB - MD5: de113c80381c87ac2465ec7e903e2e56
Documentation
Case report form (PDF, 19 pages).
Data.tab
May 23, 2025 - Replication data for Safety and efficacy of 3- and 5-day regimens of levamisole in loiasis: a randomized, placebo-controlled, double-blind clinical trial
Tabular Data - 18.8 KB - 1 Variables, 546 Observations - UNF:6:QDTu5z2Y7xIeanRSu3mpUw==
Données
Main dataset, pseudoanonymized (text UTF-8, tab-separated values).
LEV-Loa-README.txt
May 23, 2025 - Replication data for Safety and efficacy of 3- and 5-day regimens of levamisole in loiasis: a randomized, placebo-controlled, double-blind clinical trial
Plain Text - 3.1 KB - MD5: 17ef164af6d4c1a6c7466501e9c45a83
Documentation
Dataset citation, dictionnary and description.
Protocole (french)
May 23, 2025 - Replication data for Safety and efficacy of 3- and 5-day regimens of levamisole in loiasis: a randomized, placebo-controlled, double-blind clinical trial
Adobe PDF - 978.7 KB - MD5: abcbc134d5a6b7e9bd11ac8cfa781362
Documentation
Study protocol (PDF, 41 pages).
Replication data for: Revisiting the Loa loa microfilaremia thresholds above which serious adverse events may occur with ivermectin treatment (Cameroon)
Replication data for: Revisiting the Loa loa microfilaremia thresholds above which serious adverse events may occur with ivermectin treatment (Cameroon)
Mar 4, 2025
Boullé, Charlotte; Pion, Sébastien; Gardon, Jacques; Gardon-Wendel, Nathalie; Fokom Domgue, Joël; Kamgno, Joseph; Chesnais, Cédric; Boussinesq, Michel, 2025, "Replication data for: Revisiting the Loa loa microfilaremia thresholds above which serious adverse events may occur with ivermectin treatment (Cameroon)", https://doi.org/10.23708/4GVQIJ, DataSuds, V1, UNF:6:ibS817Wds6hX+S6k9UOsdg== [fileUNF]
Data: data from two clinical trials conducted in Cameroon where L. loa MFD were determined before IVM administration. References: Gardon J, Gardon-Wendel N, Demanga-Ngangue, Kamgno J, Chippaux J-P, Boussinesq M. Serious reactions after mass treatment of onchocerciasis with iverme...
IVM_SAE_dictionary.tab
Mar 4, 2025 - Replication data for: Revisiting the Loa loa microfilaremia thresholds above which serious adverse events may occur with ivermectin treatment (Cameroon)
Tabular Data - 279 B - 4 Variables, 5 Observations - UNF:6:ltQ5yZeR2M0mG6wjkbhtEA==
Documentation
Data dictionary
IVM_SAE.tab
Mar 4, 2025 - Replication data for: Revisiting the Loa loa microfilaremia thresholds above which serious adverse events may occur with ivermectin treatment (Cameroon)
Tabular Data - 259.9 KB - 6 Variables, 10506 Observations - UNF:6:tqkmhZPx/qJ/AQogYLZUNw==
Data
Revisiting the Loa loa microfilaremia thresholds above which serious adverse events may occur with ivermectin treatment
Loa_EIG_Data_Use_Agreement_Template.docx
Mar 4, 2025 - Replication data for: Revisiting the Loa loa microfilaremia thresholds above which serious adverse events may occur with ivermectin treatment (Cameroon)
MS Word - 13.1 KB - MD5: db84ac6af90cc621a2d17a2ceec01e31
Documentation
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